Financial support: This study was supported by the grant from Brain Cancer Discovery Collaboration, Cure Brain Cancer Foundation and the NHMRC scholarship. K. L. McDonald received grants from the Brain Cancer Discovery Collaboration and the Cure Brain Cancer
نویسندگان
چکیده
Sensitization of glioblastoma cells to irradiation by modulating the glucose metabolism Han Shen, Eric Hau, Swapna Joshi, Pierre J Dilda, and Kerrie L McDonald Authors and affiliations: Cure Brain Cancer Neuro-Oncology Group, Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, 2052, Australia Cancer Care Centre, St George Hospital, Kogarah, NSW 2217, Australia. Tumour Metabolism Group, Adult Cancer Program, Lowy Cancer Research Centre, Prince of Wales Clinical School, University of New South Wales, Sydney, NSW 2052, Australia *co-first author Running title: Sensitize glioblastoma cells to irradiation
منابع مشابه
Hyperglycemia and antibody titres against heat shock protein 27 in traumatic brain injury patients on parenteral nutrition
Objective(s):Hyperglycemia worsens the neuronal death induced by cerebral ischemia. Previous studies demonstrated that diabetic hyperglycemia suppressed the expression of heat shock protein 70 and 60 (HSP70 and 60) in the liver. IgG antibody titres against heat shock protein 27 (anti HSP27) were measured to determine whether hyperglycemia exacerbates ischemic brain damage by suppressing the exp...
متن کاملMeta-analysis of Incidence of Brain Cancer Among Aircrew
Introduction: Previous studies on Brain and other Nervous System Cancers (BNSC) and aircrew have shown inconsistent results, possibly due to their relatively small sample sizes; therefore, the current study aimed to increase the precision of risk estimates.Methods: Systematic searches of PubMed and Embase for pertinent studies up to August 2016 were perfo...
متن کاملPapillary thyroid cancer with metastases to brain, lung and kidney: A case of dosimetry proven privilege of surgical resection of organ metastases
A 45-year-old woman presented with a headache and visual complaints. Brain MRI revealed a large mass in the right occipital cortex. The tumor was surgically removed and pathological examination showed papillary carcinoma originating from thyroid gland. She had a history of thyroid surgery 27 years ago indicating papillary thyroid cancer with central neck lymph node involvement followed by no ad...
متن کاملDetermining the correlated factors of breast cancer recurrence by Poisson Beta-Weibull non- mixture cure model
Introduction: Therapies for many of diseases, especially cancer, have been improved significantly in the recent years, resulting in an increase in the number of patients who do not experience mortality. Therefore, the application of cure models is more suitable for survival analysis in this population than the usual survival models are. The aim of this study was to estimate the recurrence-free ...
متن کاملThe effects of cytotoxic concentration of testosterone, progesterone and estradiol on anti-metastasis CD82/KAI1 expression level in brain glioblastoma cancer cells
Background: Studies have shown that sexual steroids can affect metastasis in cancer cells of nervous system at cellular and molecular level; however, the cellular and molecular mechanism of sexual steroids action on metastasis in cancer cells of nervous system is unclear in many cases. This study aimed at investigating the effects of cytotoxic dose of testosterone, progesterone and estradiol on...
متن کامل